Spectrum Disorder in Asia

Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child’s risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment. Preconception opioid prescription was associated with 2.43 times the odds of ASD [95% confidence interval (CI) 0.99, 6.02] and 2.64 times the odds of ASD/DD with autism features (95% CI 1.10, 6.31) compared to mothers without prescriptions. Odds for ASD and ASD/DD were non-significantly elevated for first trimester prescriptions. Work exploring mechanisms and timing between peri-pregnancy opioid use and child neurodevelopment is needed.

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the grace of God

Gen. 6:9 says Noah was a righteous man, blameless in his time; Noah walked with God. God has great compassion for His creation, in fact John 3:16 says for God….

Genesis of the earth

Gen. 6:9 says Noah was a righteous man, blameless in his time; Noah walked with God. God has great compassion for His creation, in fact John 3:16 says for God….

civilization.

Gen. 6:9 says Noah was a righteous man, blameless in his time; Noah walked with God. God has great compassion for His creation, in fact John 3:16 says for God….